First Experimental Demonstration of Time-Resolved Plastic Scintillation Dosimetry On An MR-Linac

To maximize healthy tissue sparing in the presence of respiration, we previously developed MRI-guided MLC tracking for the 1.5T Unity MR-linac (Elekta AB, SWE). Dosimetric analyses were performed using film dosimetry.

2022 AAPM AM
P.Uijtewaal (1), P.Borman (1), B.Côté (2), Y.Lechasseur (2), J.Turcotte (2), S.Lambert-girard (2), P.Woodhead (1), S.Woodings (1), W.de Vries (1), R.Flores (3), S.Smith (3), B.Raaymakers (1), M.Fast (1) | Umc Utrecht, MedScint, QC, CA, Modus Medical Devices, Inc., London, ON, CA

Comparison Between the HYPERSCINT RP200 Scintillation Detector and Other Small Field Detectors for 10MV FFF SRS Beam Modelling On a VersaHD Linear Accelerator

Plastic scintillation detectors (PSDs) have advantageous dosimetric properties, including small size and energy independence, which make them ideal candidates for small field dosimetry.

2021 AAPM AM
J.Morin, JF.Cabana, M.Goulet, D.Theriault | CISSS – Chaudiere-Appalaches, Lévis, QC, CA

Implementation and validation of beam current transformer for Mobetron ultra-high dose rate electron beam monitoring using multi-detector approach

To evaluate the performance of a custom beam current transformer (BCT) as a beam monitoring tool for the Mobetron electron radiation therapy system at ultra-high dose rates (UHDR) using a multi-detector comparison.

2022 COMP ASM
G.Famulari, K.Zerouali, J.Renaud, B.Muir, JF.Aubry, F.DeBlois, JF.Carrier | Centre Hospitalier de l’Universite de Montreal (CHUM), Montreal, QC, CA, National Research Council Canada, Montreal, QC, CA

On the orientation independence of the HYPERSCINT scintillation dosimetry research platform in a MR-linac environment.

The purpose of this work was to characterize the Hyperscint scintillation dosimetry research platform in a MR-linac environment, particularly with respect to its orientation.

2022 COMP ASM
B.Côté (1), B.Raaymakers (2), S.Woodings (2), P.Uijtewaal (2), W.de Vries (2), S.Lambert-girard (1), F.Therriault-Proulx (1), M.Fast (2) | Medscint, QC, CA (1), Umc Utrecht, NL (2)

Pre-clinical and clinical evaluation of the HYPERSCINT plastic scintillation dosimetry research platform for in vivo dosimetry during radiotherapy

The purpose of this work is to evaluate the Hyperscint-RP100 scintillation dosimetry research platform (Hyperscint-RP100, Medscint Inc., Quebec, QC, Canada) designed for clinical quality assurance (QA) for use in in vivo dosimetry measurements.

J Appl Clin Med Phys. 2022
I.Schoepper (1), S.Dieterich (2), E.Alonzo Trestrail (3), M.Sean Kent (1) | Department of Radiation Oncology, University of California Davis School of Veterinary Medicine, Davis, California, USA, Department of Radiation Oncology, University of California Davis, Medical Center, Sacramento, California, USA, Pacific Crest Medical Physics, Chico, California, USA

Technical note: Characterization and practical applications of a novel plastic scintillator for online dosimetry for an ultrahigh dose rate (FLASH)

Although flash radiation therapy (FLASH-RT) is a promising novel technique that has the potential to achieve a better therapeutic ratio between tumor control and normal tissue complications, the ultrahigh pulsed dose rates (UHPDR) mean that experimental dosimetry is very challenging.

Med Phys. 2022
Y.Poirier (1,2), J.Xu (1), S.Mossahebi (1), F.Therriault-Proulx (3), A.Sawant (1) | Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, Maryland, USA, Department of Medical Physics, McGill University, Montreal, Quebec, Canada, MedScint, QC, CA

Patient Specific QA for External Beam Radiotherapy Using the HYPERSCINT Plastic Scintillation Detector

Plastic scintillation detectors (PSDs) have interesting dosimetric properties, including small size and energy independence. These advantages make them well suited for VMAT patient-specific QA, either alone or in conjunction with a detector matrix. This work aims to determine if the HYPERSCINT scintillation dosimetry research platform (Medscint inc., Quebec city, Canada) can replace the classic ion chamber in a clinical patient-specific QA workflow.

2020 AAPM AM
M.Goulet | CISSS – Chaudiere-Appalaches, Lévis, QC, CA

Characterization of the Hyperscint Dosimetry System for Real-Time Dosimetry Measurements with the Varian TrueBeamLinac

Plastic scintillator/optical fibre dosimetry systems are advantageous due to their near water equivalence, waterproof construction, linear dose response, and good spatial resolution due to their small size. The nanosecond decay times of plastic scintillators enable the possibility of real-time dosimetry. We tested the new Hyperscint?? fibre detector system to determine if, in addition to the expected dose and field size responses, this system can provide real-time dose information.

2020 AAPM AM
C.Penner (1,2), C.Hoehr (2), C.Mendez (1), C.Duzenli (1) | BC Cancer, Vancouver, BC, CA, TRIUMF, Vancouver, BC, CA

Brachytherapy Technique Commissioning Using the HYPERSCINT Plastic Scintillation Detector

Accurate dosimetry in brachytherapy is not an easy task, as most detectors exhibit volume averaging or energy dependance reducing their usability. Free from these limitations are plastic scintillation detectors (PSDs), which makes them well suited for brachytherapy applications, either for in vivo dosimetry or commissioning. This work aims to determine if the HYPERSCINT scintillation dosimetry research platform (Medscint inc., Quebec city, Canada) can be used for brachytherapy dose measurement in the context of commissioning a new brachytherapy technique.

2020 AAPM AM
M.Goulet, N.Octave, P.Duguay-drouin | CISSS – Chaudiere-Appalaches, Lévis, QC, CA

Characterization of a Novel Plastic Scintillator for Instant Real- Time Dosimetry in Electron FLASH-RT

To characterize and validate the novel Hyperscint RP100 plastic dosimeter as a direct pulse counter and investigate its use as a real-time in-vivo dosimeter in FLASH-RT radiobiological experiments.

2021 COMP ASM
Y.Poirier (1), J.Xu (1), A.Ahmady (1), S.Mossahebi (1), H.Zhang (1), F.Therriault-Proulx (2), A.Sawant (1) | University of Maryland School of Medicine, Baltimore, MD, USA , McGill University, QC, CA , MedScint, QC, CA

Precise Pulse Delivery Control Using Monitor Units in Electron FLASH-RT

In electron FLASH-RT, precise delivery of the correct number of pulses is critical to accurate dose administration in preclinical radiobiological studies. This work investigates the use of LINAC monitor ion chambers to most precisely control FLASH pulse delivery.

2021 AAPM AM
J.Xu, Y.Poirier, A.Sawant | University of Maryland School of Medicine, Baltimore, MD, USA

Novel Plastic Scintillator for Online Dosimetry in Electron FLASH-RT

The accurate delivery of electrons at FLASH-RT dose rates in radiobiological experiments require new dosimeters that are capable of accurately measuring the radiation dose delivered at >0.55 Gy per pulse (>100 Gy/s) in real-time.

2021 AAPM AM
Y.Poirier (1), J.Xu (1), A.Ahmady (1), S.Mossahebi (1), H.Zhang (1), F.Therriault-Proulx (2), A.Sawant (1) | University of Maryland School of Medicine, Baltimore, MD, USA , Medscint, QC, CA

Investigations of a Novel HyperscintTM Plastic Scintillator Detector and Hyperspectral Analysis Approach in a 74 MeV Proton Beam

A novel plastic scintillator and spectral analysis approach (Hyperscint™) was investigated in a 74 MeV proton beam for stem effect, dose and dose rate response, and suitability to provide a Cerenkov-free reference spectrum for use in MV x-ray dose calibrations.

2021 AAPM AM
C.Duzenli, C.Hoehr, C.Belanger-champagne, C.Penner, V.Strgar | BC Cancer, Vancouver, BC, CA, TRIUMF, Vancouver, BC, CA, University of British Columbia, BC, CA

EFLASH Dosimetry On a Conventional Linac Using Pulse-Gated Delivery

To build on previous experiments and improve reproducibility of electron FLASH delivery on a conventional linear accelerator, a pulse-gating circuit was constructed and tested with several dosimeters.

2021 AAPM AM
C.Duzenli, C.Mendez, M.Petric, J.Sweeney, D.Ta, T.Karan | BC Cancer, Vancouver, BC, CA

On the nature of the light produced within PMMA optical light guides in scintillation fiber-optic dosimetry

The goal of this study was to evaluate the nature of the stem effect light produced within an optical fiber, to quantify its composition, and to evaluate the efficiency of the chromatic technique to remove the stem effect.

Phys Med Biol. 2013
F.Therriault-Proulx, L.Beaulieu, L.Archambault, S.Beddar | Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA, Département de Physique, de Génie Physique et d’Optique, Université Laval, Québec, Québec, Canada, Département de Radio-Oncologie, Hôtel-Dieu de Québec, Centre Hospitalier Universitaire de Québec, Québec, Canada

On the use of a single-fiber multipoint plastic scintillation detector for 192Ir high-dose-rate brachytherapy

The goal of this study was to prove the feasibility of using a single-fiber multipoint plastic scintillation detector (mPSD) as an in vivo verification tool during (192)Ir high-dose-rate brachytherapy treatments

Med Phys. 2013
F.Therriault-Proulx, S.Beddar | Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA, Département de Physique, de Génie Physique et d’Optique, Université Laval, Québec, Québec, Canada

Development of a novel multi-point plastic scintillation detector with a single optical transmission line for radiation dose measurement

The goal of this study was to develop a novel multi-point plastic scintillation detector (mPSD) capable of measuring the dose accurately at multiple positions simultaneously using a single optical transmission line.

Phys Med Biol. 2012
F.Therriault-Proulx, L.Archambault, L.Beaulieu, S.Beddar | Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA, Département de Physique, de Génie Physique et d’Optique, Université Laval, Québec, Québec, Canada, Département de Radio-Oncologie, Hôtel-Dieu de Québec, Centre Hospitalier Universitaire de Québec, Québec, Canada

Review of plastic and liquid scintillation dosimetry for photon, electron, and proton therapy

While scintillation dosimetry has been around for decades, the need for a dosimeter tailored to the reality of modern radiation therapy-in particular a real-time, water-equivalent, energy-independent dosimeter with high spatial resolution-has generated renewed interest in scintillators over the last 10 years.

Phys Med Biol. 2016
L Beaulieu (1,2), S Beddar (3,4) | Département de physique, génie physique et optique, et Centre de recherche sur le cancer, Université Laval, Québec, CA , Département de radio-oncologie et Axe Oncologie du CRCHU de Québec, QC, CA, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, TX, USA

Water-equivalent plastic scintillation detectors for high-energy beam dosimetry: II. Properties and measurements

The properties of a new scintillation detector system for use in dosimetry of high-energy beams in radiotherapy have been measured. The most important properties of these detectors are their hgh spatial resolution and their nearly water-equivalence.

Phys Med Biol. 1992
A.S. Beddar, T.R. Mackie, F.H. Attix | Depanment of Medical Physics, University of Wisconsin Medical School, Madison, Wl, USA

Water-equivalent plastic scintillation detectors for high-energy beam dosimetry: I. Physical characteristics and theoretical consideration

A minimally perturbing plastic scintillation detector has been developed for the dosimetry of high-energy beams in radiotherapy. The detector system consists of two identical parallel sets of radiation-resistant optical fibre bundles, each connected to independent photomultiplier tubes.

Phys Med Biol. 1992
A.S. Beddar, T.R. Mackie, F.H. Attix | Depanment of Medical Physics, University of Wisconsin Medical School, Madison, Wl, USA

A method to correct for temperature dependence and measure simultaneously dose and temperature using a plastic scintillation detector

Plastic scintillation detectors (PSDs) work well for radiation dosimetry. However, they show some temperature dependence, and a priori knowledge of the temperature surrounding the PSD is required to correct for this dependence.

Phys Med Biol. 2015
F.Therriault-Proulx, L.Wooton, S.Beddar | Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA

Beam matching for small-field dosimetry applications using accelerator solenoid current and a miniature plastic scintillation detector.

The goal of this work is to determine the optimal accelerator solenoid current (ASOL) that minimizes the spread of measured small field output factor (OF) values between a series of machines.

2022 COMP ASM
L.Gingras (1), F.Beaulieu (1), M.Besnier (1), B.Côté (2), D.Leblanc (2), L.Beaulieu (1), L.Archambault (1) | CHU de Québec – Université Laval, QC, CA (1), Medscint, QC, CA (2)

FLASH Irradiation of Drosophila Melanogaster Using Low Energy X-Rays

To investigate the capability of low energy x-rays to elicit the FLASH effect, Drosophila melanogaster larvae were irradiated with ultrahigh dose-rate (UHDR) and conventional radiotherapy (CONV-RT) dose rates using an inexpensive x-ray tube system.

2022 AAPM AM
A.Hart, J.Dudzic, J.Eby, S.Perlman, M.Bazalova-Carter | University of Victoria, Victoria, BC ,CA

Orthovoltage to Monoenergetic Photon Beam Energy Correction Factor for HyperScint Scintillation Dosimeter

The HyperScint scintillator dosimetry system from MedScint is a small-field dosimeter with reported energy independence down to 100-keV. This work investigates the energy dependence of the scintillator between a monoenergetic photon source and polyenergetic orthovoltage beam.

2022 AAPM AM
B.Insley, D.Bartkoski, L.Che Fru, M.Salehpour | M.D. Anderson Cancer Center, Houston, TX

Dosimetric Characterization of the ARIEL 10 MV X-Ray Ultrahigh Dose-Rate (FLASH) Irradiation Platform at TRIUMF

To characterize the beam delivery capabilities and dose rates achievable on the new ultrahigh dose-rate (UHDR) 10MV x-ray irradiation platform at TRIUMF.

2022 AAPM AM
N.Esplen (1), L.Egoriti (2), T.Planche (3), A.Hart (1), B.Paley (3), C.Hoehr (3), A.Gottberg (3), M.Bazalova-Carter (1) | University of Victoria, Victoria, BC ,CA (1), University of British Columbia, BC, CA (2), TRIUMF, Vancouver, BC, CA (3)

Plastic Scintillation Detector for Dosimetric Characterization of Mobetron Ultra-High Dose Rate Electron Beam

To present commissioning data for the Mobetron electron radiation therapy system (IntraOp) at ultra-high dose rate (UHDR) using a plastic scintillation detector (PSD).

2022 AAPM AM
G.Famulari (1), K.Zerouali (1), O.Piron (1), JF.Aubry (1), F.DeBlois (1), JF.Carrier (2) | Centre Hospitalier de l’Universite de Montreal (CHUM), Montreal, QC, CA, Departement de Physique, Universite de Montreal, Montreal, QC, CA

A Novel Multi-Headed Scintillation Detector for Fast and Efficient Dose Measurements at Multiple Locations Simultaneously

To develop and quantify the performances of a novel multi-point scintillation detector (mPSD) having multiple heads connected to the same optical line, allowing real-time dose measurements simultaneously at 3 positions in non-contiguous space.

2022 AAPM AM
B.Lessard (1,2), Y.Lechasseur (3), S.Lambert-girard (3), F.Therriault-Proulx (3), L.Beaulieu (1,2), L.Archambault (1,2) | Département de physique, génie physique et optique, et Centre de recherche sur le cancer, Université Laval, Québec, CA , CHU de Quebec – Universite Laval, QC, CA, MedScint, QC, CA

On the Use of a Commercial Plastic Scintillation Detector for Determination of Detector-Specific Small Field Output Correction Factors of Other Detectors

The goal of this work is to determine small field output correction factors of various detectors using a commercial plastic scintillation detector as a reference and to compare values with current available data.

2022 AAPM AM
M.Besnier (1), F.Beaulieu (1), F.Berthiaume (1,2), Y.Cervantes Espinosa (1), B.Côté (2), S.Lambert-girard (1,2), D.Leblanc (1,2), Y.Lechasseur (2), F.Therriault-Proulx (2), L.Archambault (1), L.Beaulieu (1), L.Gingras (1) | CHU de Quebec – Universite Laval, QC, CA, MedScint, QC, CA

Quantifying the DNA-damaging Effects of FLASH Irradiation With Plasmid DNA

To investigate a plasmid DNA nicking assay approach for isolating and quantifying the DNA-damaging effects of ultrahigh-dose-rate (ie, FLASH) irradiation relative to conventional dose-rate irradiation.

Int J Radiat Oncol Biol Phys. 2022
A.Perstin (1), Y.Poirier (2), A.Sawant (2), M.Tambasco (3) | Department of Physics, San Diego State University, San Diego, California (1), Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, Maryland, USA (2), Department of Physics, San Diego State University, San Diego, California, USA (3)

External beam irradiation angle measurement using Cerenkov emission

Due to its angular dependency, Cerenkov light has long been considered a contamination signal in plastic scintillating dosimeters.

Med Phys. 2021
E.Jean (1,2,3), S.Lambert-girard (4), F.Therriault-Proulx (4), L.Beaulieu (1,2) | Département de physique, génie physique et optique, et Centre de recherche sur le cancer, Université Laval, Québec, CA , Département de radio-oncologie et Axe Oncologie du CRCHU de Québec, QC, CA, Département de radio-oncologie du CIUSSS-MCQ, CHAUR de Trois-Rivières, Trois-Rivières, QC, Canada, MedScint, QC, CA

Characterization of an x‐ray tube‐based ultrahigh dose‐rate system for in vitro irradiations.

To present an x-ray tube system capable of in vitro ultrahigh dose-rate (UHDR) irradiation of small < 0.3 mm samples and to characterize it by means of a plastic scintillation detector (PSD).

Med Phys. 2021
D.Cecchi (1), F.Therriault-Proulx (2), S.Lambert-girard (2), A.Hart (1), A.Macdonald (1), M.Pfleger (1), M.Lenckowski (1), M.Bazalova-Carter (1) | Department of Physics and Astronomy, University of Victoria, Victoria, British Columbia, Canada, MedScint, QC, CA

Comparative optic and dosimetric characterization of the HYPERSCINT scintillation dosimetry research platform for multipoint applications

This study introduces the HYPERSCINT research platform (HYPERSCINT-RP100, Medscint Inc., Quebec, Canada), the first commercially available scintillation dosimetry platform capable of multi-point dosimetry through the hyperspectral approach.

Phys Med Biol. 2021
E.Jean (1,2,3), F.Therriault-Proulx (4), L.Beaulieu (1,2) | Département de physique, génie physique et optique, et Centre de recherche sur le cancer, Université Laval, Québec, CA , Département de radio-oncologie et Axe Oncologie du CRCHU de Québec, QC, CA, Département de radio-oncologie du CIUSSS-MCQ, CHAUR de Trois-Rivières, Trois-Rivières, QC, Canada, MedScint, QC, CA

Pre-Clinical and Clinical Evaluation of the HYPERSCINT Scintillation Dosimetry Research Platform

The purpose of this work is to evaluate the HYPERSCINT scintillation dosimetry research platform (Medscint Inc., Quebec City, Canada) designed for clinical QA for use in in-vivo dosimetry measurements.

2020 AAPM AM
I.Schoepper, E.Trestrail, S.Dieterich, M.Kent | WR Pritchard Veterinary Medical Teaching Hospital, UC Davis School of Veterinary Medicine UC Davis School Of Veterinary Medicine, Pacific Crest Medical Physics ,Chico, CA, UC Davis Medical Center, Sacramento, CA, Surgical and Radiological Sciences, UC Davis School of Veterinary Medicine, Davis, CA

Dosimetric Characterization of the HYPERSCINT Scintillation Dosimetry Research Platform for Multipoint Applications

Multipoint detectors are very interesting toward developing new phantoms and making measurements in constrained space. This study aims at assessing the performance of the HYPERSCINT dosimetry research platform (Medscint inc., Québec, Canada) with a high spatial resolution 3-point plastic scintillation detector for application to high energy photon beam dosimetry.

2020 AAPM AM
E.Jean, F.Therriault-Proulx, L.Beaulieu | CHU de Quebec – Universite Laval, QC, CA, Medscint, QC, CA , Centre Hospitalier Univ de Québec, Québec, QC, CA

Development of An Automated Routine for Finding the Precise Location of Scintillators Elements and Their Emission Spectrum in a Multi-Point Scintillation Detector

The goal of this study is to develop an approach allowing for calibration of multi-point scintillation detector (mPSD) using only the photon beam from a linear accelerator such that it doesn’t depend on the availability of other irradiation modalities (e.g. orthovoltage irradiators). This study also aims at determining an experimental method to validate the spatial position of the different scintillators within the mPSD.

2020 AAPM AM
B.Lessard (1,2), F.Larose (1,2), F.Berthiaume (1,2,3), S.Lambert-girard (1,2,3), F.Therriault-Proulx (3), L.Archambault (1,2) | Département de physique, génie physique et optique, et Centre de recherche sur le cancer, Université Laval, Québec, CA , CHU de Quebec – Universite Laval, QC, CA, MedScint, QC, CA

Feasibility of Plastic Scintillator Dosimeters for FLASH Therapy

To examine the capabilities of plastic scintillator dosimeters (PSDs) to accurately measure FLASH radiotherapy dose rates delivered with an x-ray tube.

2020 AAPM AM
D.Cecchi (1), F.Therriault-Proulx (2), M.Bazalova-Carter (1) | University of Victoria, Victoria, BC ,CA,, Medscint, QC, CA

Development and characterization of an optical fiber-based Cerenkov dosimeter

This study introduces a novel hybrid Cerenkov-scintillation dosimeter

2021 COMP ASM
E.Jean (1,2,3), S.Lambert-girard (3), F.Therriault-Proulx (3), L.Beaulieu (1,2) | CHU de Quebec – Universite Laval, QC, CA, Département de radio-oncologie et Axe Oncologie du CRCHU de Québec, QC, CA, MedScint, QC, CA

Small field dosimetry of a Varian TrueBeam High Definition MLC linear accelerator using theHyperscint RP200 scintillation detector.

To evaluate the performance of the new Hyperscint RP200 plastic scintillator for small field measurements of a Varian TrueBeam linear accelerator in comparison with the current state-of-the-art methodology in the clinic.

2021 COMP ASM
L.Gingras, B.Côté, F.Berthiaume, S.Lambert-Girard, D.Leblanc, L.Archambault, L.Beaulieu, F.Therriault-Proulx | CHU de Quebec – Universite Laval, QC, CA, Département de radio-oncologie et Axe Oncologie du CRCHU de Québec, QC, CA, MedScint, QC, CA

Development of a Novel Hybrid Scintillation-Cerenkov Detector for Simultaneous Dose and Irradiation Angle Measurements

This study introduces a novel hybrid detector capable of simultaneous dose and direct irradiation angle measurements based on Cerenkov angular dependency.

2021 AAPM AM
E.Jean (1,2), S.Lambert-girard (3), F.Therriault-Proulx (3), L.Beaulieu (1) | CHU de Quebec – Universite Laval, QC, CA, CHAUR, Trois-Rivieres, QC, CA , MedScint, QC, CA

Plastic and Lead-Doped Scintillators for Ultrahigh Dose-Rate Irradiations Delivered with An X-Ray Tube

To examine the capabilities of plastic scintillators of different compositions to accurately measure dose in high dose-rate dose irradiations delivered with an x-ray tube.

2021 AAPM AM
D.Cecchi (1), C.Gigeure (2), F.Larose (2), F.Therriault-Proulx (3), L.Beaulieu (2), M.Bazalova-Carter (1) | University of Victoria, Victoria, BC ,CA,, CHU de Quebec – Universite Laval, QC, CA, MedScint, QC, CA