Performance of the HYPERSCINT scintillation dosimetry research platform for the 1.5 T MR-linac

This study demonstrates the suitability of the HYPERSCINT PSD for accurate time- resolved dosimetry measurements in the 1.5 T MR-linac. The excellent performance during continuous MR scanning and during dynamic movement indicates the great potential of the detector to validate end-to-end workflows of online adaptive radiotherapy

Prescilla Uijtewaal (1), Benjamin Côté (2), Thomas Foppen (1), J H Wilfred de Vries (1), Simon J Woodings (1), Pim T S Borman (1), Simon Lambert-Girard (2), François Therriault-Proulx (2), Bas W Raaymakers (1), Martin F Fast (1) | 1 – UMC Utrecht, Netherland, 2 – Medscint, Canada

Investigation of temperature dependence of inorganic scintillators using the HYPERSCINT research platform

The temperature dependence of four inorganic scintillation detectors was examined spectrally using the HYPERSCINT Research Platform 200 under 6 MV photon irradiations from a LINAC. After varying only the temperature of the detectors, all scintillators demonstrated linearity when the change in photon counts with temperature in the full-width at half maximum of their spectrum are integrated. Establishing the magnitude of the temperature dependence of the materials is critical to decide whether correction factors are required. This is especially true in applications such as brachytherapy, where detectors equilibrise to body temperature.

Radiation Measurements
Owen McLaughlin (1), Michael Martyn (1,2), Christoph Kleefeld (1), Mark Foley (1) | 1. Physics Unit, School of Natural Sciences, University of Galway, Galway, Ireland, 2. Galway Clinic, Doughiska, Galway, Ireland

Plastic scintillation detectors: real-time dosimetry in the MR-Linac environment.

Optical innovation meets clinical translation : in the vanguard of adaptive MR/RT research effort, the UMC Utrecht research team works with plastic scintillation detectors to bring MR-Linac treatment to the next level.

| UMC Utrecht, Medscint

Plastic scintillation detectors ready to shine as FLASH radiotherapy gathers momentum.

The team of University of Victoria’s XCITE Lab are using plastic scintillation detectors to provide real-time, small-field dosimetry in their FLASH radiotherapy experiments.

| University of Victoria – XCITE Lab, Medscint

First Experimental Demonstration of Time-Resolved Plastic Scintillation Dosimetry On An MR-Linac

In this study, UMC Utrecht research team demonstrates the feasibility of a hybrid experimental setup combining an innovative multipoint scintillator detector with film in a moving phantom quantifying MLC tracking for lung SBRT. The prototype cassette is capable of measuring dose (with film and 4 points scintillators simultaneously) during motion experiments, combining film dosimetry with time-resolved and absolute dosimetry.

P.Uijtewaal (1), P.Borman (1), B.Côté (2), Y.Lechasseur (2), J.Turcotte (2), S.Lambert-girard (2), P.Woodhead (1), S.Woodings (1), Vries (1), R.Flores (3), S.Smith (3), B.Raaymakers (1), M.Fast (1) | 1 – UMC Utrecht, Netherland, 2 – Medscint, Canada, 3 – Modus Medical Devices, Canada

Implementation and validation of beam current transformer for Mobetron ultra-high dose rate electron beam monitoring using multi-detector approach

To evaluate the performance of a custom beam current transformer (BCT) as a beam monitoring tool for the Mobetron electron radiation therapy system at ultra-high dose rates (UHDR) using a multi-detector comparison (plastic scintillators, ion chamber and film).

G.Famulari (1), K.Zerouali (1), J.Renaud (2), B.Muir (1), JF.Aubry (1), F.DeBlois (1), JF.Carrier (1) | 1 – Centre Hospitalier de l’Universite de Montreal (CHUM), Montreal, QC, CA, 2 – National Research Council Canada, Montreal, QC, CA

Pre-clinical and clinical evaluation of the HYPERSCINT plastic scintillation dosimetry research platform for in vivo dosimetry during radiotherapy

The purpose of this work is to evaluate the HYPERSCINT HS-RP100 scintillation dosimetry research platform designed for clinical quality assurance (QA) for use in in vivo dosimetry measurements. The device correctly detected the treatment error when the heads were intentionally laterally shifted. In three canine clinical patients treated in multiple fractions.

J Appl Clin Med Phys. 2022
I.Schoepper (1), S.Dieterich (2), E.Alonzo Trestrail (3), M.Sean Kent (1) | Department of Radiation Oncology, University of California Davis School of Veterinary Medicine, Davis, California, USA, Department of Radiation Oncology, University of California Davis, Medical Center, Sacramento, California, USA, Pacific Crest Medical Physics, Chico, California, USA

Technical note: Characterization and practical applications of a novel plastic scintillator for online dosimetry for an ultrahigh dose rate (FLASH)

Although FLASH radiation therapy is a promising novel technique, the ultrahigh pulsed dose rates mean that experimental dosimetry is very challenging. The plastic scintillator shows a linear and reproducible response and is able to accurately measure the radiation absorbed dose delivered by 16-MeV electrons at UHPDR. The dose is measured accurately in real time with a greater level of precision than that achieved with a radiochromic film.

Med Phys. 2022
Y.Poirier (1,2), J.Xu (1), S.Mossahebi (1), F.Therriault-Proulx (3), A.Sawant (1) | 1- Department of Radiation Oncology, University of Maryland School of Medicine, Maryland, USA, 2- Department of Medical Physics, McGill University, Quebec, Canada, 3- MEDSCINT, Quebec, Canada

Characterization of the HYPERSCINT Dosimetry System for Real-Time Dosimetry Measurements with the Varian TrueBeamLinac

Plastic scintillator/optical fibre dosimetry systems are advantageous due to their near water equivalence, waterproof construction, linear dose response, and good spatial resolution due to their small size. The nanosecond decay times of plastic scintillators enable the possibility of real-time dosimetry. We tested the new HYPERSCINT fibre detector system to determine if, in addition to the expected dose and field size responses, this system can provide real-time dose information. The HYPERSCINT system is suitable after appropriate calibration to be used to measure relative dose delivered in cGy as well as indicate changing dose conditions within 0.3 seconds.

2020 AAPM AM
C.Penner (1,2), C.Hoehr (2), C.Mendez (1), C.Duzenli (1) | BC Cancer, Vancouver, BC, CA, TRIUMF, Vancouver, BC, CA

Characterization of a Novel Plastic Scintillator for Instant Real- Time Dosimetry in Electron FLASH-RT

Purpose was to characterize and validate the novel HYPERSCINT RP100 plastic dosimeter as a direct pulse counter and investigate its use as a real-time in-vivo dosimeter in FLASH-RT radiobiological experiments. In conclusions, the HYPERSCINT RP100 dosimeter accurately measured the delivered radiation absorbed dose under both characterization and biological experimental conditions, with a higher degree of reliability than conventional radiochromic film. Furthermore, its 500 Hz measurement frequency could directly and accurately measure the number of pulses delivered in real time. This shows its potential for real-time in-vivo dosimetry to verify accurate delivery during biological experiments and clinical treatments.

Y.Poirier (1), J.Xu (1), A.Ahmady (1), S.Mossahebi (1), H.Zhang (1), F.Therriault-Proulx (2), A.Sawant (1) | 1- University of Maryland School of Medicine, MD, USA , 2- McGill University, QC, Canada, 3- MEDSCINT, QC, Canada