Implementation and validation of beam current transformer for Mobetron ultra-high dose rate electron beam monitoring using multi-detector approach

To evaluate the performance of a custom beam current transformer (BCT) as a beam monitoring tool for the Mobetron electron radiation therapy system at ultra-high dose rates (UHDR) using a multi-detector comparison.

G.Famulari, K.Zerouali, J.Renaud, B.Muir, JF.Aubry, F.DeBlois, JF.Carrier | Centre Hospitalier de l’Universite de Montreal (CHUM), Montreal, QC, CA, National Research Council Canada, Montreal, QC, CA

Technical note: Characterization and practical applications of a novel plastic scintillator for online dosimetry for an ultrahigh dose rate (FLASH)

Although flash radiation therapy (FLASH-RT) is a promising novel technique that has the potential to achieve a better therapeutic ratio between tumor control and normal tissue complications, the ultrahigh pulsed dose rates (UHPDR) mean that experimental dosimetry is very challenging.

Med Phys. 2022
Y.Poirier (1,2), J.Xu (1), S.Mossahebi (1), F.Therriault-Proulx (3), A.Sawant (1) | Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, Maryland, USA, Department of Medical Physics, McGill University, Montreal, Quebec, Canada, MedScint, QC, CA

Characterization of a Novel Plastic Scintillator for Instant Real- Time Dosimetry in Electron FLASH-RT

To characterize and validate the novel Hyperscint RP100 plastic dosimeter as a direct pulse counter and investigate its use as a real-time in-vivo dosimeter in FLASH-RT radiobiological experiments.

Y.Poirier (1), J.Xu (1), A.Ahmady (1), S.Mossahebi (1), H.Zhang (1), F.Therriault-Proulx (2), A.Sawant (1) | University of Maryland School of Medicine, Baltimore, MD, USA , McGill University, QC, CA , MedScint, QC, CA

Precise Pulse Delivery Control Using Monitor Units in Electron FLASH-RT

In electron FLASH-RT, precise delivery of the correct number of pulses is critical to accurate dose administration in preclinical radiobiological studies. This work investigates the use of LINAC monitor ion chambers to most precisely control FLASH pulse delivery.

2021 AAPM AM
J.Xu, Y.Poirier, A.Sawant | University of Maryland School of Medicine, Baltimore, MD, USA

Novel Plastic Scintillator for Online Dosimetry in Electron FLASH-RT

The accurate delivery of electrons at FLASH-RT dose rates in radiobiological experiments require new dosimeters that are capable of accurately measuring the radiation dose delivered at >0.55 Gy per pulse (>100 Gy/s) in real-time.

2021 AAPM AM
Y.Poirier (1), J.Xu (1), A.Ahmady (1), S.Mossahebi (1), H.Zhang (1), F.Therriault-Proulx (2), A.Sawant (1) | University of Maryland School of Medicine, Baltimore, MD, USA , Medscint, QC, CA

EFLASH Dosimetry On a Conventional Linac Using Pulse-Gated Delivery

To build on previous experiments and improve reproducibility of electron FLASH delivery on a conventional linear accelerator, a pulse-gating circuit was constructed and tested with several dosimeters.

2021 AAPM AM
C.Duzenli, C.Mendez, M.Petric, J.Sweeney, D.Ta, T.Karan | BC Cancer, Vancouver, BC, CA

FLASH Irradiation of Drosophila Melanogaster Using Low Energy X-Rays

To investigate the capability of low energy x-rays to elicit the FLASH effect, Drosophila melanogaster larvae were irradiated with ultrahigh dose-rate (UHDR) and conventional radiotherapy (CONV-RT) dose rates using an inexpensive x-ray tube system.

2022 AAPM AM
A.Hart, J.Dudzic, J.Eby, S.Perlman, M.Bazalova-Carter | University of Victoria, Victoria, BC ,CA

Dosimetric Characterization of the ARIEL 10 MV X-Ray Ultrahigh Dose-Rate (FLASH) Irradiation Platform at TRIUMF

To characterize the beam delivery capabilities and dose rates achievable on the new ultrahigh dose-rate (UHDR) 10MV x-ray irradiation platform at TRIUMF.

2022 AAPM AM
N.Esplen (1), L.Egoriti (2), T.Planche (3), A.Hart (1), B.Paley (3), C.Hoehr (3), A.Gottberg (3), M.Bazalova-Carter (1) | University of Victoria, Victoria, BC ,CA (1), University of British Columbia, BC, CA (2), TRIUMF, Vancouver, BC, CA (3)