Characterization of a novel time-resolved, real-time scintillation dosimetry system (HYPERSCINT RP-FLASH) for ultra-high dose rate radiation therapy applications

4. FLASH-RT / UHDR, MeV Electron, Beam characterization, Commissioning, Detector comparaison, Energy Dependency, LINAC Pulse Discrimination, Quality Assurance, Real-time Dosimetry Show more

This study evaluates a novel scintillation dosimetry solution developed by Medscint for ultra-high dose rate (UHDR) radiotherapy, the HYPERSCINT RP-FLASH. The system was tested on an UHDR electron beamline, demonstrating dose linearity and independence from dose rate (1.8–1341 Gy/s) and dose per pulse (0.005–7.68 Gy) within ±3% tolerance. The system accurately measured doses per pulse up to 120 Hz.

With daily calibrations and specific correction factors, the system provides real-time, millisecond-resolved dosimetric measurements for pulsed conventional and UHDR beams, showing promise for applications in FLASH-RT.

PREPRINT
Alexander Baikalov (1,2,3), Daline Tho (1), Kevin Liu (1,4), Stefan Bartzsch (2,3), Sam Beddar (1,4), Emil Schüler (1,4) | 1. University of Texas MD Anderson Cancer Center, Houston, TX – USA, 2. Technical University of Munich – Germany, 3. German Research Center for Environmental Health, Neuherberg – Germany, 4. The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences, Houston, TX – USA

Characterization of a 0.8 mm³ Medscint Plastic Scintillator Detector System for Small Field Dosimetry

1. Small-Field Dosimetry, MeV Electron, Advanced Optical Dosimetry, Angular dependancy, Beam characterization, Detector comparaison, Energy Dependency, Quality Assurance Show more

The scintillator-based dosimetry system HYPERSCINT RP-200, coupled with a 0.8 mm³ plastic scintillator detector, demonstrated excellent dosimetric properties for small field radiation therapy, including good repeatability, dose linearity, and accuracy down to field sizes as small as 0.5 × 0.5 cm².

Physics in Medicine & Biology
Elena Timakova (1,2), Magdalena Bazalova-Carter (1) , Sergei Zavgorodni (2) | 1. University of Victoria, British Columbia, Canada, 2. BC Cancer Agency, Vancouver Island Centre, British Columbia, Canada

Performance of the HYPERSCINT scintillation dosimetry research platform for the 1.5 T MR-linac

2. Adaptive-RT (ex. MR-LINAC), 3. Treatment Plan (End-to-End) QA, MV Photon, Adaptive-RT, Angular dependancy, Detector comparaison, Energy Dependency, Quality Assurance, Real-time Dosimetry Show more

This study demonstrates the suitability of the HYPERSCINT PSD for accurate time- resolved dosimetry measurements in the 1.5 T MR-linac. The excellent performance during continuous MR scanning and during dynamic movement indicates the great potential of the detector to validate end-to-end workflows of online adaptive radiotherapy

PHYSICS IN MEDICINE & BIOLOGY
Prescilla Uijtewaal (1), Benjamin Côté (2), Thomas Foppen (1), J H Wilfred de Vries (1), Simon J Woodings (1), Pim T S Borman (1), Simon Lambert-Girard (2), François Therriault-Proulx (2), Bas W Raaymakers (1), Martin F Fast (1) | 1 – UMC Utrecht, Netherland, 2 – Medscint, Canada

Use of a Commercial Plastic Scintillation Detector for Determination of Detector-Specific Small Field Output Correction Factors of Other Detectors

1. Small-Field Dosimetry, MV Photon, Commissioning, Detector comparaison, Monte Carlo Simulations, Quality Assurance Show more

The goal of this work is to determine small field output correction factors of various detectors using the HYPERSCINT plastic scintillation detector as a reference and to compare values with current available data. The simple and well understood composition and geometry of the scintillation detector make it ideal to be used as a reference detector for the evaluation of field output correction factors. Field size dependent correction factors have been extracted for different detectors and show limited discrepancies with current available data. This may potentially be attributed to inter detector variability or other methodological uncertainties in published data.

2022 AAPM ANNUAL MEETING
M.Besnier (1), F.Beaulieu (1), F.Berthiaume (1,2), Y.Cervantes Espinosa (1), B.Côté (2), S.Lambert-girard (1,2), D.Leblanc (1,2), Y.Lechasseur (2), F.Therriault-Proulx (2), L.Archambault (1), L.Beaulieu (1), L.Gingras (1) | 1- CHU de Quebec – Universite Laval, QC, Canada, 2- MEDSCINT, QC, Canada

Plastic scintillation detectors ready to shine as FLASH radiotherapy gathers momentum.

1. Small-Field Dosimetry, 4. FLASH-RT / UHDR, 9. Advanced Dosimetry, MeV Electron, MV Photon, Beam characterization, Fundamental Research, LINAC Pulse Discrimination, Quality Assurance, Real-time Dosimetry Show more

The team of University of Victoria’s XCITE Lab are using plastic scintillation detectors to provide real-time, small-field dosimetry in their FLASH radiotherapy experiments.

PHYSICS WORLD
| University of Victoria – XCITE Lab, Medscint

First Experimental Demonstration of Time-Resolved Plastic Scintillation Dosimetry On An MR-Linac

2. Adaptive-RT (ex. MR-LINAC), MV Photon, Adaptive-RT, Custom Probe Development, Quality Assurance, Real-time Dosimetry Show more

In this study, UMC Utrecht research team demonstrates the feasibility of a hybrid experimental setup combining an innovative multipoint scintillator detector with film in a moving phantom quantifying MLC tracking for lung SBRT. The prototype cassette is capable of measuring dose (with film and 4 points scintillators simultaneously) during motion experiments, combining film dosimetry with time-resolved and absolute dosimetry.

2022 AAPM ANNUAL MEETING
P.Uijtewaal (1), P.Borman (1), B.Côté (2), Y.Lechasseur (2), J.Turcotte (2), S.Lambert-girard (2), P.Woodhead (1), S.Woodings (1), W.de Vries (1), R.Flores (3), S.Smith (3), B.Raaymakers (1), M.Fast (1) | 1 – UMC Utrecht, Netherland, 2 – Medscint, Canada, 3 – Modus Medical Devices, Canada

Comparison Between the HYPERSCINT RP200 Scintillation Detector and Other Small Field Detectors for 10MV FFF SRS Beam Modelling On a VersaHD Linear Accelerator

1. Small-Field Dosimetry, 7. Commissioning, MV Photon, Angular dependancy, Beam characterization, Commissioning, Detector comparaison, Energy Dependency, Quality Assurance Show more

Plastic scintillation detectors (PSDs) have advantageous dosimetric properties, including small size and energy independence, which make them ideal candidates for small field dosimetry.

2021 AAPM ANNUAL MEETING
J.Morin, JF.Cabana, M.Goulet, D.Theriault | CISSS – Chaudiere-Appalaches, Lévis, QC, CA

Implementation and validation of beam current transformer for Mobetron ultra-high dose rate electron beam monitoring using multi-detector approach

4. FLASH-RT / UHDR, MeV Electron, Beam characterization, Commissioning, Quality Assurance, Real-time Dosimetry Show more

To evaluate the performance of a custom beam current transformer (BCT) as a beam monitoring tool for the Mobetron electron radiation therapy system at ultra-high dose rates (UHDR) using a multi-detector comparison (plastic scintillators, ion chamber and film).

2022 COMP ANNUAL SCIENTIFIC MEETING
G.Famulari (1), K.Zerouali (1), J.Renaud (2), B.Muir (1), JF.Aubry (1), F.DeBlois (1), JF.Carrier (1) | 1 – Centre Hospitalier de l’Universite de Montreal (CHUM), Montreal, QC, CA, 2 – National Research Council Canada, Montreal, QC, CA

On the orientation independence of the HYPERSCINT scintillation dosimetry research platform in a MR-linac environment.

2. Adaptive-RT (ex. MR-LINAC), MV Photon, Adaptive-RT, Angular dependancy, Commissioning, Quality Assurance Show more

The purpose of this work was to characterize the HYPERSCINT scintillation dosimetry research platform in a MR-linac environment, particularly with respect to its orientation. This study shows that the HYPERSCINT scintillation dosimetry platform can be used regardless of its orientation in a magnetic field environment. Together with its linearity to dose and dose-rate, the detector shows great promises for development of dosimetry solutions dedicated to the MR-Linac environment.

2022 COMP ANNUAL SCIENTIFIC MEETING
B.Côté (1), B.Raaymakers (2), S.Woodings (2), P.Uijtewaal (2), W.de Vries (2), S.Lambert-girard (1), F.Therriault-Proulx (1), M.Fast (2) | Medscint, Canada (1), UMC Utrecht, Netherland (2)

Pre-clinical and clinical evaluation of the HYPERSCINT plastic scintillation dosimetry research platform for in vivo dosimetry during radiotherapy

5. In Vivo Dosimetry, MV Photon, Quality Assurance, Real-time Dosimetry Show more

The purpose of this work is to evaluate the HYPERSCINT HS-RP100 scintillation dosimetry research platform designed for clinical quality assurance (QA) for use in in vivo dosimetry measurements. The device correctly detected the treatment error when the heads were intentionally laterally shifted. In three canine clinical patients treated in multiple fractions.

J Appl Clin Med Phys. 2022
I.Schoepper (1), S.Dieterich (2), E.Alonzo Trestrail (3), M.Sean Kent (1) | Department of Radiation Oncology, University of California Davis School of Veterinary Medicine, Davis, California, USA, Department of Radiation Oncology, University of California Davis, Medical Center, Sacramento, California, USA, Pacific Crest Medical Physics, Chico, California, USA